Ruben Vidal Selected Research

Apoferritins

1/2016	Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy.
7/2014	A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation.
1/2013	Abnormal iron homeostasis and neurodegeneration.
5/2012	A mutant light-chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage.
7/2010	Accumulation of oxidative DNA damage in brain mitochondria in mouse model of hereditary ferritinopathy.
1/2010	Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
8/2009	Clinical phenotype and neuroimaging findings in a French family with hereditary ferritinopathy (FTL498-499InsTC).
5/2009	Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene.
11/2008	Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration.
1/2008	Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice.

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Ruben Vidal Research Topics

Disease

24	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 02/2004
19	Alzheimer Disease (Alzheimer's Disease) 10/2021 - 02/2004
13	Neuroferritinopathy 01/2019 - 01/2008
8	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2021 - 03/2002
6	familial Danish Dementia 10/2020 - 03/2002
6	Dementia (Dementias) 07/2020 - 02/2004
5	Amyloid Plaque 01/2022 - 08/2005
5	Amyloidosis 01/2022 - 03/2002
4	Tauopathies 01/2022 - 11/2010
4	Nervous System Heredodegenerative Disorders 11/2020 - 08/2004
3	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2022 - 05/2009
2	Gliosis 07/2020 - 01/2009
2	Neuroinflammatory Diseases 07/2020 - 03/2010
2	Pick Disease of the Brain (Pick's Disease) 01/2020 - 01/2018
2	Atrophy 11/2018 - 08/2009
2	Movement Disorders (Movement Disorder) 01/2016 - 01/2008
2	Iron Overload 01/2016 - 01/2008
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 10/2022
1	Frontotemporal Dementia (Semantic Dementia) 10/2022
1	TDP-43 Proteinopathies 01/2022
1	Synucleinopathies 01/2022
1	Proteostasis Deficiencies 01/2021
1	Chronic Traumatic Encephalopathy 01/2020
1	Corticobasal Degeneration 01/2020
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2020
1	Immunoglobulin Light-chain Amyloidosis 04/2015
1	Seizures (Absence Seizure) 01/2015
1	Restless Legs Syndrome (Restless Legs) 01/2015
1	Inflammation (Inflammations) 07/2012
1	Osteomalacia 11/2011
1	Iron Deficiencies 11/2011
1	Autosomal Dominant Hypophosphatemic Rickets 11/2011
1	Leukoencephalopathies 08/2009
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 05/2009
1	Scrapie 05/2009
1	Neuroblastoma 02/2004
1	Oligodendroglioma 02/2004
1	Glioblastoma (Glioblastoma Multiforme) 02/2004
1	Brain Neoplasms (Brain Tumor) 02/2004
1	Neuroepithelial Neoplasms (Gliomatosis Cerebri) 02/2004

Drug/Important Bio-Agent (IBA)

17	Amyloid (Amyloid Fibrils)IBA 01/2022 - 03/2002
13	IronIBA 11/2020 - 01/2008
12	Peptides (Polypeptides)IBA 05/2012 - 02/2004
10	ApoferritinsIBA 01/2016 - 01/2008
9	Ferritins (Ferritin)IBA 01/2019 - 01/2008
7	tau Proteins (tau Protein)IBA 10/2021 - 01/2018
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2002
4	LigandsIBA 10/2021 - 01/2021
3	Prion ProteinsIBA 01/2022 - 05/2009
3	Protein Isoforms (Isoforms)IBA 01/2021 - 05/2009
2	ThiophenesIBA 10/2021 - 01/2021
2	PresenilinsIBA 07/2012 - 11/2008
2	NucleotidesIBA 11/2010 - 11/2008
2	Presenilin-1IBA 03/2008 - 08/2005
1	DNA-Binding Proteins (DNA Binding Protein)IBA 10/2022
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	DecorinIBA 01/2022
1	benzothiazoleIBA 10/2021
1	Nonsense Codon (Nonsense Mutation)IBA 01/2021
1	Amyloidogenic ProteinsIBA 01/2021
1	Apolipoproteins E (ApoE)IBA 07/2020
1	LipidsIBA 07/2020
1	CholesterolIBA 07/2020
1	GoldIBA 11/2018
1	Coloring Agents (Dyes)IBA 11/2018
1	Isoflurophate (DFP)FDA Link 01/2016
1	Single-Chain AntibodiesIBA 04/2015
1	EpitopesIBA 04/2015
1	Immunoglobulin G (IgG)IBA 04/2015
1	Biomarkers (Surrogate Marker)IBA 07/2014
1	Complementary DNA (cDNA)IBA 07/2012
1	Fibroblast Growth Factor-23IBA 11/2011
1	Membrane Proteins (Integral Membrane Proteins)IBA 11/2009
1	PrionsIBA 05/2009
1	Flavin-Adenine Dinucleotide (FAD)IBA 11/2008
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 03/2008
1	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 02/2004
1	anti-GFAP autoantibodiesIBA 02/2004
1	Messenger RNA (mRNA)IBA 02/2004
1	AntibodiesIBA 02/2004
1	Transcription Factors (Transcription Factor)IBA 02/2004
1	Amyloid beta-PeptidesIBA 03/2002

Therapy/Procedure

2	Therapeutics 01/2021 - 01/2008
1	Chelation Therapy (Therapy, Chelation) 01/2016